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KMID : 0357919850190020150
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Korean Journal of Pathology
1985 Volume.19 No. 2 p.150 ~ p.155
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An Experimental Study on the Influence of DDVP upon the Kidney
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Abstract
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With the progress of farming and foresting, the demand of agricultural pesticide has
been remarkably increased and accordingly, its intoxication has been widely publicized.
Among the pesticides, organophosphorus chemicals has been believed to be almost
nontoxic because they are not accumulative in the tissue.
This study is attempted to examine the effects of DDVP which has been used most
frequently on the kidney. And they were divided into normal and experimental groups.
The results obtained from this experiment are as follows
1) BUN, serum creatinine are increased in the group of DDVP administered while
serum cholinesterase is suppresed significantly.
2) Microscopically, swelling and degeneration of tubular cells and hyaline casts in
tubules. Ultrastructually swelling of mitochondria, partial fragmentation of cristae and
electron dense bodies in the kidney are observed in the group of DDVP administered.
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KEYWORD
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